The group of Peter van Lent, Dept. of Experimental Rheumatology has significantly contributed to the elucidation of the role of alarmins S100A8/A9 in inflammation and joint destruction in rheumatoid arthritis and osteoarthritis.
In close cooperation with the Dept. of Immunology in Munster, Germany it was found that these proteins can be used as a biomarker for biomolecular imaging of local inflammatory activity which was recently published in Nature communications 5:4593, 2014.
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